XERF - Structural Skin Tightening

Welcome to Structural Skin Tightening

The next step in the evolution of skincare is here. It’s Structural Skin Tightening—A treatment that delivers all the skin tightening, collagen-boosting power of radiofrequency, with no numbing, needles, or downtime. Just visible results, backed by science and designed for comfort. Unlike conventional RF treatments, the XERF™ treatment delivers energy deeper into the skin—reaching the shallow, middle, and deep layers—where real change begins.

Results without sacrifice

No numbing, no needles, and no downtime.
True skin transformation at every level, delivering energy exactly where you need it most.
Fully customizable treatments that adapt to each patient’s unique skin profile.

How XERF Structural Skin Tightening works

The XERF system offers the world’s first multifrequency monopolar RF treatment. By combining both 6.78 MHz and 2 MHz frequencies, XERF can deliver energy not just deeper, but exactly where you need it most, creating smoother and tighter skin.

The XERF system leverages Wave Fit™ pulse and Advanced Integrated Cryogen Delivery cooling technology to control energy delivery while maintaining surface temperature, for a Never-Numb™ treatment. XERF sessions require a shorter room time vs. similar treatments that require numbing, potentially increasing the number of patients that can be treated per day.

A treatment as unique as you are

No two individuals are alike, and their skin treatments shouldn’t be either. The XERF system adapts to each patient’s unique skin profile using Accurate Impedance Feedback for real-time analysis of the skin. With three depth settings and ten intensity levels, a XERF treatment is a truly personalized experience tailored for each individual patient.

Before and after 2 treatments. Courtesy of Dianne Quibell, MD

Before and after 4 weeks, Courtesy of Jordan Wang, MD, MBE, MBA

Before and after 2 treatments. Courtesy of Dianne Quibell, MD

The world’s first multifrequency monopolar RF treatment, The XERF Structural Skin Tightening treatment delivers energy into each patient’s skin exactly where they need it most. No needles, no numbing, and no downtime – just smoother and tighter skin, personalized for each patient.

Clinical Evidence

Monopolar radiofrequency for dermal temperature regulation and remodeling: A porcine model study

Download Study

Efficacy of dual-frequency noninvasive monopolar radiofrequency in skin tightening

Download Article

FAQs

What internal temperatures are created by the XERF system, and how were they measured?

In in-vivo studies, Cynosure Lutronic measured internal skin temperatures of 50°C, 60°C, and 70°C using ultrasound-guided fiber-optic imaging. Following the XERF treatment, histological analysis confirmed collagen remodeling.

How do you know XERF treatments strengthen collagen and tighten the skin?

Histological evidence from in-vivo porcine studies shows increased thickening and tightening of collagen bundles at multiple tissue depths, along with an observable upward pull in the fascia.

How do you know how deeply the XERF system delivers RF energy?

Histological analysis from multiple clinical studies confirms the XERF system delivers RF energy to the SMAS (Superficial Musculoaponeurotic System). The SMAS is a foundational tissue layer beneath the skin that plays a key role in lifting and tightening sagging skin and reducing the appearance of jowls.

Intended for distribution in the United States only.

The XERF device is intended for use in dermatologic and general surgical procedures for electrocoagulation and hemostasis.

All instances of the term “skin tightening” are used to describe tightening effects that occur via soft tissue coagulation.

Cynosure, LLC and Lutronic Aesthetic, Inc. do not diagnose or treat medical conditions, prescribe treatment protocols, provide medical advice, or otherwise practice medicine. Patients should consult with a qualified healthcare professional for diagnosis and proper treatment protocols/parameters to determine if treatment with any product is right for them. Qualified healthcare professionals are responsible for diagnosis and treatment protocols using products.